Beating cancer with Gremlins

Beating cancer

with Gremlins

Beating cancer with Gremlins

 

Stand Up To Cancer scientist, Professor Simon Leedham, is supporting research into an entirely new treatment option for people with bowel cancer, by investigating a molecule called GREMLIN1. Despite its scary name, GREMLIN1 plays an important in our bodies and is produced by healthy stromal cells that surround the gut lining.

However, because bowel cancer originates from the bowel lining, bowel tumours are also surrounded by stromal cells. It’s thought that bowel cancer cells can hijack their surrounding stromal cells and cause them to make way too much GREMLIN1. This creates an environment in which bowel cancer cells can thrive.

Simon is developing a drug to target the surround stromal cells, rather than just the tumour on its own, to help bring the production of GREMLIN1 back under control - ultimately providing a new way to treat bowel cancer.

100% OF THE MONEY YOU RAISE HELPS FUND LIFE-SAVING RESEARCH

LEARN MORE