WHO YOUR MONEY HELPS

100% of the money you raise will go towards funding 30 translational research trials and projects that take clever scientific ideas and turns them into life-saving medicines and tests, faster.

Get inspired! Read stories from our supporters and get to know our superstar scientists and their research – then get fundraising and join the rebellion.

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EVE

Eve was diagnosed with Stage 4 Ewing’s Sarcoma in July 2015, aged 9, and underwent a year of treatment including chemotherapy and radiotherapy. In June 2016, she was told the tumour had gone, but relapsed the following month and restarted chemotherapy.

55% of people diagnosed with bone sarcoma in England survive their disease for ten years or more. And thanks to breakthroughs in research, mortality rates for bone sarcoma are projected to fall by 23% in the UK between 2014 and 2035.

CLINICAL TRIAL: PlasmaMATCH

No two cancers are identical, so finding the perfect treatment for each patient can be difficult. PlasmaMATCH, a Cancer Research UK project supported by the Stand Up To Cancer campaign is analysing blood samples from breast cancer patients to identify mistakes in cancer’s DNA. By tracking patient’s progress, scientists hope to spot genetic mistakes unique to each patient that will predict how a cancer will behave. This information could then be used to design a blood test that will help doctors choose the most effective treatment for each individual patient.

ANNA

Anna’s mum was diagnosed with breast cancer when she was 34. She sadly passed away at the age of 61 in 2009 after the cancer spread to her liver. Then, just three years after her mum’s death and when she was only 31 herself, Anna was diagnosed with breast cancer too.

“I regularly checked myself and I thought it was just a gland when I went to the GP. But at the hospital appointment I knew it was cancer.”

Anna had chemotherapy and surgery, as well as tamoxifen and Herceptin, and took part in a clinical trial.

JOSH

Josh was diagnosed with Wilms’ tumour before he was two years old. Josh said: "I don't want anyone else to have cancer like me" 

Josh needed chemotherapy followed by two operations to remove one of his kidneys and part of his lung, then radiotherapy and more chemotherapy. Karen said: “Even when he was sick during the treatment, he carried on like nothing was wrong.” Josh is now six and he enjoys football and computer games.

CLINICAL TRIAL: InPACT

Because cancer of the penis is so rare, it is very hard to study. And so penis cancer treatments have not improved as much as those for other cancers. Astonishingly, doctors still don’t know which treatments are most effective for this disease. Dr Steve Nicholson hopes to set this right. With a revolutionary new trial design funded by Stand Up To Cancer, Dr Nicholson hopes to transform the way we treat penis cancer - identifying the best standard of care for the next generation.

NEIL

Former deputy chief fire officer Neil was diagnosed with cancer of the penis in August 2015. Neil, who has two children, went to the GP after spotting a rash on his penis which was not getting better.

“The day I was told I had cancer just sent me into a different world. The word cancer filled me with fear. I had never heard of penis cancer, and had no idea how I would get through it. I had two major operations, including partial amputation and reconstructive surgery.”

“I am keen that people become aware of signs and symptoms. I come from a work environment where men sometimes don’t share their concerns.”

DR STEVEN NICHOLSON

Dr Nicholson is the UK lead of the penis cancer group, which is part of the international rare cancer initiative. As a clinician scientist, Steve is looking to improve the way we treat penile cancer. Because this disease is so rare, it is very difficult to know which the best treatment is. Steve is hoping to find out whether giving chemotherapy or chemotherapy and radiation together before surgery can help improve patient survival. With so little known about treating this disease, Steve’s work is desperately needed.

PROFESSOR DEAN FENNELL

Professor Fennell is one of our Stand Up To Cancer Researchers. He and his team at the University of Leicester work on lung cancers, particularly mesothelioma, a cancer caused by asbestos. Despite our best efforts, this disease is currently incurable and Professor Fennell hopes to change that.

Dr Dean Fennel is testing an exciting new way of activating the immune system to recognise and treat this cancer. Mesothelioma cells produce a molecule called PD-1 that prevents the immune system from attacking them. By using a drug that seeks out and sticks to PD-1, Dr Fennel hopes to re-awakening the white blood cells and leaving them free to attack the tumour. This could open up a new way of treating this deadly disease.

CLINICAL TRIAL: HOPON

Treating head and neck cancers can sometimes have unpleasant side effects, damaging the jaw and teeth. The HOPON trial is looking to see whether introducing a high-pressure oxygen chamber to the treatment room might help patients like Eileen heal the damage to their jaws, allowing them to have the dentistry they need and to get on with enjoying life.

EILEEN

Eileen was diagnosed with mouth cancer in January 2013 after she had found a lump in her throat.

Eileen, who has three sons and eight grandchildren, said: “I had surgery on 25th March and then radiotherapy. I had already had a denture for my lower teeth, but the radiotherapy affected my jaw so that didn’t fit any more. I was without my bottom teeth for 18 months as a result.”

“I went on the SU2C-funded HOPON trial which might have helped my jaw heal better. Now I have a beautiful smile – it has been a long journey and very difficult at times.” 

KEZIA

In February 2012, Kezia was diagnosed with a germ cell tumour, a rare type of tumour that develops from reproductive cells. Kezia, now 16, had chemotherapy and three major operations, which included surgery on one of her ovaries and her liver.

“During my treatment I had five operations including three major ones. But the hardest part for me was having chemotherapy where I lost all my hair.

“Four years on, I'm doing amazingly! All my hair has grown back and I'm back at school, although I do still have check-ups.  I couldn't have got this far without my amazing friends and my family who have been through just as much as me!”

 

JAMIE

Jamie, 25, was diagnosed with an inoperable brain tumour in January 2015 and told he may only have 3-5 years to live. He has undergone months of radiotherapy and chemotherapy and hopes to go travelling once his treatment finishes.

Brain cancer survival is improving and has doubled in the last 40 years in the UK. But  despite this amazing progress only around a fifth (19%) of people diagnosed with brain cancer in England and Wales survive their disease for five years or more. That’s why finding new ways to treat brain cancer is one of our priorities and we’re driving research progress in this area.

DR VICKY COYLE

Dr Vicky Coyle is a clinical senior lecturer and medical oncologist at Queen’s University in Belfast. Vicky is a specialist in bowel cancer. For many people with this disease, their treatment is initially successful only for the cancer to return.  Stand up to cancer are supporting Vicky to test a new idea that might help improve the survival for people with bowel cancer. Vicky is leading the UK part of a huge Canadian-led multinational study to see whether routine physical exercise could prevent this cancer from returning. If this study is successful, it could change the way people are treated worldwide as well as changing NHS and government policy.